Water Ionizers and reviews from Alkaline Water Plus Skip to main content

Hydrogen Water [Ionized Water] Research

Hydrogen water & ionized water research in clinical trials

Hydrogen Water and Ionized Water: Proven to Support Healing and Wellness

Thousands of scientific studies have shown that ionized water, hydrogen water, and molecular hydrogen (H2) can support the prevention and management of many chronic conditions. The research below highlights the growing body of evidence confirming the therapeutic power and reliability of molecular hydrogen—whether infused in water or inhaled as gas.

Jump to Research: Heart | Cancer | Respiratory | Stroke | Brain-Nerves | Diabetes | Kidneys | Liver | Cholesterol | Intestines-Stomach | Meals | Skin | Inflammation | Oxidation | Aging | Eyes | Other | Videos & Discussion

What Is Electrolyzed Hydrogen Water (EHW)?

Electrolyzed Hydrogen Water (also known as ionized water or electrolyzed water) is the most common and convenient way to consume hydrogen. It’s safe, easy to make at home, and offers a wide range of health benefits—for both people and pets.

When you drink water from a water ionizer, you’re not just hydrating—you’re supplying your body with molecular hydrogen (H2), one of nature’s most powerful antioxidants. These hydrogen molecules help fight harmful free radicals throughout your body.

Unlike gases that simply dissolve, hydrogen is infused into the water during electrolysis. Once consumed, it circulates through the bloodstream, reaching deep into the cells. Hydrogen-rich water acts quickly—comparable to inhaling hydrogen gas—but remains in the body longer, offering extended antioxidant benefits.

This antioxidant activity helps reduce inflammation and oxidative stress, promoting cellular health and natural healing. Scientific studies show that hydrogen-infused water provides both preventive and therapeutic support, with benefits that can last for days after drinking.

Understanding Electrolysis

Electrolysis is the process your water ionizer uses to split ordinary water into two parts—alkaline and acidic. Think of it like the two poles of a magnet: one side creates alkaline, antioxidant-rich water filled with molecular hydrogen (H2).

This hydrogen-infused alkaline water has fascinated scientists for decades for its remarkable safety and effectiveness. During electrolysis, hydrogen gas is not simply dissolved—it becomes part of the water itself, creating a potent and therapeutic drink.

Hydrogen Gas vs. Hydrogen Water

Some people use hydrogen gas machines for inhalation, which has shown positive results in research studies. However, these systems require caution and proper use, as overexposure could stress the lungs. Hydrogen gas acts quickly but is expelled from the body within a few hours.

By contrast, drinking hydrogen-rich water provides a more gradual and sustained release of benefits throughout the body, making it a safer and more practical choice for daily use.

Why Add Molecular Hydrogen to Your Daily Routine?

Adding molecular hydrogen to your daily routine may help slow the effects of aging, reduce inflammation, and support overall vitality. Extensive research continues to confirm that hydrogen-rich water can protect and rejuvenate nearly every organ system in the body.

The Most Effective Way to Consume Hydrogen (H2)

Scientific evidence consistently shows that drinking electrolyzed hydrogen water (ionized water) delivers more comprehensive health benefits than inhaling hydrogen gas. It’s the simplest and most effective way to experience hydrogen’s healing potential.

Hydrogen Water vs. Regular Water

Regular water (H2O) naturally contains hydrogen, but it’s chemically bound and cannot act as an antioxidant. In contrast, hydrogen-rich water contains free hydrogen molecules that neutralize harmful free radicals and combat oxidative stress.

Explore the many studies and testimonials showing how alkaline, ionized, and hydrogen-infused water can enhance overall wellness.

This website is dedicated to sharing credible evidence—from clinical research to real customer experiences—about the health benefits of hydrogen water. See my personal testimonial here.

How Molecular Hydrogen Works in the Body

Molecular hydrogen is small enough to pass through cell membranes—even crossing the blood-brain barrier—to neutralize free radicals at the source. This deep cellular access supports mental clarity, DNA protection, and faster recovery from oxidative damage.

Hydrogen’s tiny size and lipid solubility make it a unique antioxidant that can reach areas other antioxidants cannot. It also evaporates harmlessly, leaving no toxic residue in the body.

Hydrogen: The Foundation of Life

Hydrogen (H2) and oxygen combine to create water—the essence of all life. However, too much oxidation in the body disrupts this balance and leads to what scientists call oxidative stress—a root cause of aging and disease.

Excess oxygen can become unstable, forming harmful “active oxygen” molecules or free radicals. Even a small amount of molecular hydrogen can safely neutralize these radicals and restore balance.

Learn more about the science of molecular hydrogen here.

What Customers Say About Hydrogen Water

“Since drinking hydrogen water, I’ve noticed I sleep better and feel less sore. My morning stiffness is gone.” — Ian S.

“Hydrogen water gives me steady energy throughout the day and helps me sleep better at night. It even speeds recovery after workouts.” — Peter

"I used to have a problem with eczema. I would break out with a rash all over my hands, sometimes on my face, and all that has cleared up." Liliana S.

"We're drinking Hydrogen Water, and I just had a report on my wife's cancer markers. All three of my wife's cancer markers went down since we started drinking Hydrogen water." Aldo P.

"I love it! I have more energy, and my skin looks better!!" Cynthia N.

"I'm obsessed with my water machine. It has helped improve my mood, and my skin looks even better than it used to. I think it helps with hangovers, too." Ashley Y.

"I was feeling lousy for many years, and I narrowed it down to the water quality at my job .. now I feel great." Matthew B.

How Do You Get Hydrogen Water?

There are two main ways to get hydrogen water:

  1. Ionized Water (water ionizer)
  2. Hydrogen Water (hydrogen water machine)

My personal preference is for the water ionizer because the variety of high-pH water is a tool I use to help balance the pH of my body. However, I also frequently use a hydrogen water machine. I consider these machines as tools. Just as a carpenter uses the best tools to build a long-lasting strong house, I use these tools to build a long-lasting healthy body.

Scientific Studies & Clinical Trials on Hydrogen and Ionized Water Benefits

Thousands of scientific studies and clinical trials have demonstrated the health benefits of electrolyzed hydrogen water (EHW), hydrogen water (HW), and hydrogen gas. New research continues to emerge regularly. To explore these studies yourself, try searching online using terms like “EHW PUBMED” or include “nih.gov” to locate official publications on scientific databases such as PubMed.

Below are selected examples of peer-reviewed studies showing how hydrogen water and ionized water support heart health and may play a role in preventing or improving cardiovascular conditions.

*Note: EHW is also referred to by scientists as ionized water, electrically reduced water, electrochemically reduced water, electrolyzed reduced water, reduced water, or ERW.

Hydrogen Research Related to Heart Health

Studies show that hydrogen-rich water can help protect the heart by reducing oxidative stress and inflammation—two major causes of heart disease. Molecular hydrogen acts as a selective antioxidant, neutralizing harmful free radicals that damage heart tissue. Numerous studies have examined how molecular hydrogen affects the heart. Research indicates that hydrogen may help reduce blood pressure, improve cardiac function, dissolve cholesterol deposits, reduce left ventricular hypertrophy, and lower mortality rates following cardiac arrest.

Heart disease hydrogen water research chart

Read the full article on this topic: 2 Ways Ionized Water Combats Heart Disease

Year Topic / Subject Title & Key Findings
2000–2024 Blood Pressure

Use of Ionized Water in Hypochlorhydria or Achlorhydria – Prof. Kuninaka Hironage, Head of Kuninaka Hospital

After 2–3 months of drinking alkaline antioxidant water, blood pressure gradually dropped due to the water’s ability to dissolve cholesterol in the blood vessels.

2017 Myocardial Infarction The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction – First human pilot study shows that hydrogen inhalation is safe and improves hypertension markers.
2019 Hypertension Hydrogen Gas Improves Left Ventricular Hypertrophy in Dahl Rats with Salt-Sensitive Hypertension – Animal study showing hydrogen reduces high blood pressure and heart muscle thickening.
2018 Chronic Heart Failure Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure – Hydrogen reduced oxidative stress and symptoms of heart failure in animal models.
2016 Cardiac Arrest Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function After Cardiac Arrest – Animal study shows hydrogen enhances heart recovery and neurological outcomes.
2015 Cardiac Dysfunction Treatment with Hydrogen Molecule Attenuates Cardiac Dysfunction in Diabetic Mice – Animal study found hydrogen improved heart function and reduced diabetes-related cardiac damage.
2015 Atherosclerosis Molecular Hydrogen Stabilizes Atherosclerotic Plaque – Animal study showing hydrogen reduces arterial plaque instability and supports vascular health.
2012–2014 Cardiac Arrest

Hydrogen Inhalation Improves Neurological Outcomes After Cardiac Arrest – Hydrogen treatment improved recovery after resuscitation.

H₂ Gas Improves Functional Outcome After Cardiac Arrest – Hydrogen reduced mortality and improved survival rates.

2018 Vascular Aging Hydrogen-Rich Water Prevents Vascular Aging of the Aorta – Study found hydrogen reduced cholesterol and markers of arterial aging in mice.

Hydrogen Research Related to Cancer

Scientific studies indicate that hydrogen water and ionized water may help slow cancer progression and support better outcomes for cancer patients. Research in both human clinical trials and animal models highlights hydrogen’s powerful antioxidant, anti-inflammatory, and cellular protective effects, making it a promising area for cancer prevention and adjunctive therapy.

Hydrogen water and cancer research chart

Mice Experiments on Hydrogen and Cancer

Read the transcript here: Ionized Water Mice Experiments Transcript. Learn more about ionized water benefits for cancer and disease.

Year Topic / Subject Title & Key Findings
2019 Colorectal Cancer Hydrogen Gas Restores Exhausted CD8+ T Cells in Patients with Advanced Colorectal Cancer – Human study shows hydrogen therapy reversed immune imbalances caused by chemotherapy and improved outcomes in stage IV colorectal cancer patients.
2017 Colorectal Cancer (Liver Protection) Protective Effect of Hydrogen-Rich Water on Liver Function of Colorectal Cancer Patients Treated with Chemotherapy – Randomized clinical trial showed hydrogen water alleviates liver injury caused by chemotherapy.
2018 Lung Cancer Hydrogen Gas Inhibits Lung Cancer Progression Through Targeting SMC3 – Animal study demonstrates that hydrogen suppresses lung cancer growth.
2017 Colon Cancer Hydrogen Water Enhances 5-Fluorouracil-Induced Inhibition of Colon Cancer – Animal study shows hydrogen water improved survival rates and enhanced the anticancer effects of chemotherapy.
2013 Mitochondria & Cancer Mitochondria and Cancer: Past, Present and Future – Review summarizes research highlighting mitochondria’s major role in cancer development and progression.
2009 Reducing Chemotherapy Side Effects Molecular Hydrogen Alleviates Nephrotoxicity Induced by the Anti-Cancer Drug Cisplatin – Animal study found hydrogen protects against kidney toxicity caused by chemotherapy, without reducing the drug’s anticancer effects.

Hydrogen Research on Chronic Lower Respiratory Disease

Studies indicate that hydrogen water helps reduce inflammation, support immune balance, and protect lung tissue from oxidative and environmental stress. These findings suggest hydrogen has potential as a therapeutic aid for respiratory and inflammatory conditions.

Hydrogen water and respiratory health research chart

Year Topic / Subject Title & Key Findings
2017 Anti-Inflammatory (Rhinitis) Effect of Hydrogen-Rich Saline on CD4+ CD25+ Foxp3+ Treg Cells in Allergic Rhinitis Model – Animal study shows hydrogen reduces allergic inflammation and supports immune regulation.
2017 Anti-Inflammatory (Oxygen Therapy) Hydrogen Alleviates Oxygen-Induced Acute Lung Injury via SIRT1 Regulation – Animal study found hydrogen protects lungs against hyperoxia-related damage and reduces pulmonary edema.
2015 Anti-Inflammatory (Exercise) Hydrogen-Rich Water Inhibits Mitochondrial Oxidative Stress and Inflammation After Exercise – Animal study shows hydrogen reduces inflammation and oxidative stress following intense physical activity.
2009 Immune Function Immunological Effects of Electrolyzed Reduced Water on Infection in Mice – Animal study indicates hydrogen water enhances immune responsiveness against infection.

HYDROGEN RESEARCH ON STROKE

Scientific studies demonstrate that hydrogen water and hydrogen gas therapy can help protect the brain and nervous system against oxidative stress, improve recovery rates after stroke, and reduce the severity of neurological damage. Molecular hydrogen supports the body’s natural antioxidant defenses, helping preserve brain cells, arteries, and mitochondrial function.

stroke-prevention.jpg

Year Topic / Subject Title & Key Findings
2019 Glioblastoma Molecular hydrogen suppresses glioblastoma growth via inducing glioma stem-like cell differentiationAnimal study: Hydrogen inhalation reduced tumor growth in common brain cancer models.
2018 Traumatic Brain Injury Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathwayAnimal study: Hydrogen water showed neuroprotective and antioxidant effects in brain trauma.
2018 Spinal Cord Injury Inhalation of hydrogen ameliorates spinal cord injury in mice by protecting neurons and mitochondriaAnimal study: Hydrogen inhalation reduced cell death and preserved mitochondrial structure.
2018 Post-Stroke Neuronal Damage Hydrogen exerts neuroprotective effects on OGD/R-damaged neurons via PINK1/Parkin signaling pathwayAnimal study: Hydrogen protected neurons by regulating mitochondrial repair and reducing oxidative injury.
2018 Cerebral Ischemia / Stroke Hydrogen inhalation improves neurological outcomes after cerebral ischemia/reperfusionAnimal study: Hydrogen improved neurological recovery following stroke.
2018 Severe Brain Injury Neuroprotective effects of hydrogen inhalation in intracerebral hemorrhage modelAnimal study: Hydrogen reduced brain tissue damage and improved functional outcomes after hemorrhage.
2017 Cerebral Infarction (Acute) Hydrogen gas inhalation treatment in acute cerebral infarction: A randomized controlled clinical studyHuman study: Patients with acute stroke showed improved recovery and no adverse effects from hydrogen inhalation.
2017 Neuroblastoma Cells Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell deathCell study: Hydrogen pre-treatment prevented H2O2-induced damage in human nerve cells.
2016 Brain Injury Effect of hydrogen-rich water on angiogenesis and nerve function after traumatic brain injuryAnimal study: Hydrogen promoted new blood vessel growth and improved recovery.
2016 Brain Infarction Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injuryAnimal study: Hydrogen reduced brain infarct size and oxidative damage.
2016 Brain Damage Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injuryAnimal study: Hydrogen reduced swelling and inflammation in injured brain tissue.
2015 Neuroprotective Hydrogen activates Nrf2/HO-1 pathway in ischemia reperfusion rat modelAnimal study: Hydrogen protected brain tissue by activating antioxidant defense mechanisms.
2015 Stroke (Hypertensive Model) Hydrogen improves neurological function by attenuating blood-brain barrier disruption in stroke-prone ratsAnimal study: Hydrogen water improved neurological recovery after stroke.
2015 Protects Against Stroke Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteinsAnimal study: Hydrogen water reduced brain infarct volume and improved neurological function.

HYDROGEN RESEARCH ON ALZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

Scientific studies show that hydrogen water protects neurons, reduces memory impairments, decreases the size of brain tumors, and mitigates the severity of multiple sclerosis. Regular consumption of hydrogen-rich water or molecular hydrogen may support brain health and cognitive function.

Hydrogen water brain health

Year Topic / Condition Title & Key Findings
2013 Parkinson's Disease Pilot study of H2 therapy in Parkinson's disease: A randomized double‐blind placebo‐controlled trial — Human trial shows hydrogen water is safe, well tolerated, and significantly improves symptoms compared to control.
2019 Vascular Dementia FoxO1-mediated autophagy in hydrogen-treated rat model of vascular dementia — Animal study shows hydrogen water inhibits neuron loss and alleviates memory impairments.
2019 Glioblastoma Molecular hydrogen suppresses glioblastoma growth via glioma stem-like cell differentiation — Animal study shows inhaling hydrogen reduces common brain tumor growth.
2018 Mitochondria / Spinal Cord Injury Inhalation of hydrogen protects spinal cord neurons from apoptosis and oxidative injury — Animal study shows neuroprotective effects and mitochondrial recovery after spinal cord injury.
2018 Mild Cognitive Impairment Effects of molecular hydrogen on mild cognitive impairment — Animal study shows hydrogen water suppresses dementia and oxidative stress.
2018 Cognitive Impairment Hydrogen-rich water improves cognitive function in APP/PS1 mice without affecting Aβ clearance — Animal study shows significant improvement in cognitive behavior and reduced oxidative stress, with more pronounced effects in females.
2015 Multiple Sclerosis Hydrogen-rich water improves neurological recovery in experimental autoimmune encephalomyelitis mice — Animal study shows hydrogen delays onset and reduces severity of induced multiple sclerosis.
2015 Alzheimer's Disease Hydrogen-rich water attenuates amyloid β-induced cytotoxicity via Sirt1-FoxO3a activation — Animal study shows reduced reactive oxygen species–induced cell death and enhanced cellular repair.
2014 Age-Related Neurological Diseases Electrochemically Reduced Water protects neural cells from oxidative damage — Animal study shows hydrogen water protects neurons against oxidative stress.

HYDROGEN RESEARCH ON DIABETES

Extensive research shows that hydrogen-rich water helps improve blood glucose control, insulin sensitivity, and overall metabolic health. These studies highlight its potential in supporting diabetes management.

Hydrogen water for diabetes

Transcript of research video

50 Years of Research Highlighting the Healing Power of Ionized Water

Japan’s use of water ionizers in research and healthcare is remarkable. The Japanese enjoy some of the longest lifespans and lowest infant mortality rates in the world, potentially linked to their use of hydrogen-rich water.

Watch the video and read this article:

Ionized Water, Molecular Hydrogen & the History of Japanese Healthcare

Ionized Water Used to Treat Diabetic Necrosis

Video Transcript

Year Topic / Condition Title & Key Findings
2008 Diabetes – Glucose Tolerance Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance — Human study shows hydrogen reduces oxidative stress, improves insulin resistance, and enhances glucose metabolism.
2013 Diabetes – Glucose Uptake Hydrogen improves glycemic control in Type 1 diabetic animal model by promoting glucose uptake into skeletal muscle — Animal study shows hydrogen enhances glucose control.
2011 Diabetes – Pt Nanoparticles Anti-diabetes effect of water containing hydrogen molecules and Pt nanoparticles — Animal study shows hydrogen and nano platinum improve glucose signaling pathways.
2006 Diabetes – Anti-diabetic Effects Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice — Animal study shows hydrogen improves blood glucose control.
2006 Diabetes – Beta Cell Protection Preservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice — Animal study shows hydrogen improves glucose tolerance, increases insulin, and reduces blood glucose levels.
2005 Diabetes – Beta Cell Protection Protective mechanism of reduced water against alloxan-induced pancreatic beta-cell damage: Scavenging effect against reactive oxygen species — Animal study shows hydrogen enhances beta-cell glucose sensitivity and protects pancreatic cells from oxidative damage.

HYDROGEN RESEARCH ON KIDNEYS

Hydrogen-rich water supports kidney health, improves outcomes for dialysis patients, and protects the kidneys from damage caused by oxidative stress or toxins.

Hydrogen water supporting kidney health

Read the full article on kidney health: Damaged Kidneys? How to Repair Them Naturally

Year Topic / Condition Title & Key Findings
2018 Dialysis Novel hemodialysis (HD) treatment employing molecular hydrogen (H2)-enriched dialysis solution improves prognosis of chronic dialysis patients: A prospective observational study — Human study over 3 years shows hydrogen-enriched dialysis solution improves prognosis and overall health of dialysis patients.
2003 Kidney Disease Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water — Human study demonstrates ionized water reduces oxidative stress, improving overall kidney health in dialysis patients.
2018 Toxicity Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice — Animal study shows ionized water protects kidneys from chemotherapy-induced damage.
2017 Renal Injury & Fibrosis Hydrogen-rich water attenuates renal injury and fibrosis by regulating Transforming Growth Factor — Animal study shows hydrogen water reduces development of kidney fibrosis.
2010 Renal Injury Intake of water with high levels of dissolved hydrogen (H2) suppresses ischemia-induced cardio-renal injury in Dahl salt-sensitive rats — Animal study shows hydrogen water aids healing after kidney injury.
2014 Renal Injury Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats — Animal study shows hydrogen water helps reduce kidney injury caused by hypertension.

HYDROGEN RESEARCH ON LIVER

Hydrogen-rich water reduces oxidative stress, protects liver function, and may help prolong life.

Read the full article on liver health: Natural Healing of the Liver

Year Topic / Condition Title & Key Findings
2017 Chemo: Liver Protection Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy — Human study shows H2 helps maintain microcirculation and mitochondrial health during chemotherapy.
2011 Radiotherapy for Liver Tumors Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors — Human study demonstrates reduced stress markers associated with radiation therapy.
2013 Chronic Hepatitis B Effect of Hydrogen‐Rich Water on Oxidative Stress, Liver Function, and Viral Load in Patients with Chronic Hepatitis B — Human study shows hydrogen water alleviates oxidative stress in Hepatitis B patients.
2018 Liver Injury Post-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death — Animal study shows hydrogen preserves microcirculation and mitochondrial function, reducing liver cell death after injury.
2018 Liver & Cholesterol Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice — Animal study shows hydrogen water improves intestinal health, cholesterol metabolism, and liver protection.
2017 Liver Injury Inhalation of high concentrations of hydrogen ameliorates liver ischemia/reperfusion injury through A2A receptor mediated PI3K-Akt pathway — Animal study shows high-concentration hydrogen improves liver function and protects against ischemia/reperfusion injury.
2017 Sepsis Protection Pre-administration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury — Animal study shows hydrogen water prolongs life and reduces oxidative stress and liver cell death in sepsis.
2009 Liver Protection Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice — Animal study shows hydrogen-rich water protects the liver against chemical-induced damage.

HYDROGEN RESEARCH ON CHOLESTEROL

Hydrogen-rich water helps reduce cholesterol buildup in blood vessels and supports healthy lipid metabolism.

Year Topic / Focus Title & Key Findings
2013 Cholesterol Balance Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome — Human study shows that drinking hydrogen water supports healthy cholesterol levels.
2018 Liver & Cholesterol Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice — Animal study shows hydrogen water supports gut fermentation, which benefits cholesterol metabolism.

HYDROGEN RESEARCH ON INTESTINES & STOMACH

Hydrogen-rich water supports gut flora, improves symptoms of diarrhea and irritable bowel syndrome, and protects intestines from chemotherapy or radiation damage. Read more: The Stomach, Digestion, and Alkaline Ionized Electrolyzed Water.

Best Practices for Drinking Alkaline or Hydrogen-Rich Water

  • Before meals: Sip small amounts of water 15–30 minutes before eating. Adding a few drops of apple cider vinegar can help prepare digestion.
  • During meals: Drink moderately to aid swallowing and activate digestive enzymes. Alkaline water with a squeeze of lemon can enhance nutrient absorption, especially water-soluble vitamins (B and C) and minerals.
  • After meals: Continue with small sips for up to 30 minutes after eating to support ongoing digestion.
  • Between meals: Ideal for hydration, neutralizing metabolic acids, supporting bowel movements, and providing antioxidants if the water is rich in molecular hydrogen.

Water itself does not trigger digestion, as it has no calories. Hydrogen-rich water quickly delivers antioxidants and pH buffering benefits directly to your cells, maximizing its protective effects.

Avoid Possible Negative Effects During Meals:

Avoid drinking large amounts of water during meals, as it may temporarily dilute stomach acid, potentially slowing protein digestion.

Year Topic / Subject Title & Key Findings
2019 Gut Flora Effects of the long-term consumption of hydrogen-rich water on the antioxidant activity and the gut flora in female juvenile soccer players from Suzhou, China – Human study shows hydrogen-rich water was healthy for gut flora.
2019 Gastrointestinal Symptoms Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms – Human study shows alkaline ionized water relieves abdominal complaints and improves rest and morning energy.
2018 Irritable Bowel Syndrome with Diarrhea Effects of Alkaline-Reduced Drinking Water on Irritable Bowel Syndrome with Diarrhea: A Randomized Double-Blind, Placebo-Controlled Pilot Study – Human study shows alkaline ionized water improved symptoms of diarrhea and irritable bowel syndrome.
2005 Intestinal Health Selective stimulation of the growth of anaerobic microflora in the human intestinal tract by electrolyzed reducing water – Human study shows alkaline ionized water helps balance gut microflora.
2018 Protects Good Bacteria Intestinal Microbiota Ecological Response to Oral Administrations of Hydrogen-Rich Water and Lactulose in Female Piglets Fed a Fusarium Toxin-Contaminated Diet – Animal study shows hydrogen water protects intestinal microbiota balance.
2018 Intestinal Environment Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice – Animal study shows alkaline ionized water benefits intestinal microbes.
2018 GI Toxicity Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota – Animal study shows hydrogen-rich water protects intestines and improves prognosis during radiation.
2017 Inflammatory Bowel Disease Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression – Animal study shows hydrogen-rich water protects against inflammatory bowel disease.
1996 Intestinal Health Physiological effects of alkaline ionized water: Effects on metabolites produced by intestinal fermentation – Animal study shows alkaline ionized water supports intestinal health.

HYDROGEN RESEARCH ON SKIN

Hydrogen-rich water has been shown to alleviate psoriasis, skin ulcers, atopic dermatitis, and reduce wrinkle formation.

Hydrogen water for skin health

Year Topic / Focus Title & Key Findings
2018 Psoriasis Positive effects of hydrogen-water bathing in patients of psoriasis and parapsoriasis en plaques — Human study showing hydrogen water bathing benefits psoriasis.
2013 Skin Ulcers Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on skin cells in vitro — Human study showing hydrogen water aids skin cell reconstruction.
2012 Skin Diseases Hydrogen(H2) treatment for acute erythematous skin diseases: feasibility study — Human study showing hydrogen improved skin inflammation prognosis.
2012 Wrinkles Hydrogen-rich warm water reduces UVA-induced wrinkles and promotes collagen production — Human study shows hydrogen water helps prevent UVA-related wrinkle formation.
2013 Dermatitis Hydrogen water effects on atopic dermatitis in NC/Nga mice — Animal study shows hydrogen water benefits atopic dermatitis.

Hydrogen Research on Anti-Inflammatory Effects

Hydrogen reduces inflammation, edema, and supports immune response.

Year Topic / Subject Study & Key Findings
2014 Sports-Related Injuries Effectiveness of oral and topical hydrogen for sports injuries – Faster recovery in professional athletes.
2017 Allergic Rhinitis Hydrogen-rich saline affects Treg cells in allergic rhinitis guinea pigs – Reduces allergic inflammation.
2017 Pancreatitis Hydrogen protects mice against chronic pancreatitis – Prevents and reduces inflammation.
2017 Lung Injury Hydrogen alleviates hyperoxic acute lung injury in rats – Protective against oxygen-induced lung injury.
2016 Arthritis Molecular hydrogen decelerates rheumatoid arthritis progression – Slows disease progression.
2001 Liver Anti-inflammatory properties of molecular hydrogen – Reduces liver inflammation.
2009 Immune System Immunological effects of electrolyzed reduced water in mice – Supports immune responsiveness.

HYDROGEN RESEARCH ON ANTI-OXIDANT

Year Topic / Focus Title & Key Findings
2012 Platelets Hydrogen may inhibit collagen-induced platelet aggregation: ex vivo & in vivo study — Human and animal study showing hydrogen may inhibit platelet aggregation.
2016 Antioxidant Effects of hydrogenized water on antioxidant biomarkers, glucose uptake, insulin signaling, SIRT1, and telomerase activity — In vitro study shows commercial hydrogen water is effective as an antioxidant.
2017 Bone Health Hydrogen reduces oxidative stress and apoptosis in steroid-induced osteonecrosis — Animal study shows hydrogen prevents bone damage.
2011 Eyes - Cornea Hydrogen and N-acetyl-L-cysteine prevent oxidative stress-induced angiogenesis in cornea — Animal study shows hydrogen prevents blindness from alkali burns.
2017 Obesity Hydrogen-rich water reduces oxidative stress and body weight gain in rats on high-fat diet — Animal study shows hydrogen reduces obesity-related oxidative stress.
2011 Obesity & Diabetes Molecular hydrogen improves obesity and diabetes via hepatic FGF21 and energy metabolism in db/db mice — Animal study shows hydrogen improves energy metabolism, obesity, and diabetes.

Hydrogen Research on Anti-Aging

Hydrogen improves cell function, longevity, and protects DNA.

Year Topic / Subject Study & Key Findings
2018 Senescence-Associated Cells Hydrogen alleviates cellular senescence via ROS/p53/p21 pathway – Animal study.
2017 Anti-Aging & Cell Death Hydrogen protects against oxidative damage – Animal study.
2016 Longevity Alkaline Water and Longevity: A Murine Study – 3-year survival study in mice.
2010 Bones Hydrogen prolongs lifespan of bone marrow stromal cells – In vitro study.
2013 Lifespan Electrolyzed-reduced water increases lifespan in C. elegans – Animal study.
1997 DNA Protection Electrolyzed-reduced water scavenges radicals and protects DNA – Animal study.

Hydrogen Research on Eyes

Year Topic / Subject Study & Key Findings
2019 Retinal Vein Occlusion Hydrogen gas protects against retinal edema – Animal study.
2011 Cornea Hydrogen prevents blindness in alkali-burn model – Animal study.
2010 Retina Hydrogen-loaded eye drops protect retina in ischemia-reperfusion injury – Animal study.

Other Applications of Hydrogen/Ionized Water

This section highlights various studies over the years showing the therapeutic and protective benefits of hydrogen-rich and ionized water for multiple health conditions.

Year Topic/Subject Link Title / Description of Scientific Article
Spanning over 30 years Gynecology Use of Ionized water for gynecological conditions — Prof. Watanabe Ifao, Watanabe Hospital.
"Ionized alkaline antioxidant water improves body constituents and ensures effective healing to many illnesses. In pre-eclamptic toxemia cases, results show healthier babies with stronger muscles and above-average intelligence when mothers consumed antioxidant water."
2011 Radiotherapy PubMed Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors. [Randomized human study shows therapeutic benefits before, during, and after radiation treatment.]
2011 Weight Loss HighBeam Daily consumption of 2 liters of electrolyzed water for 2 months in four obese subjects. [Average weight loss 12 pounds; increased toxin excretion observed without introducing external toxins.]
2016 Blood Viscosity BioMed Central Effect of electrolyzed high-pH alkaline water on blood viscosity in healthy adults. [Human study shows improved hydration and blood viscosity after exercise compared to purified water.]
2018 Pregnancy: Protective Benefits for Newborns PubMed Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model. [Animal study shows maternal H2 intake protects newborns.]
2017 Hemorrhagic Shock PubMed Hydrogen gas inhalation inhibits progression to the "irreversible" stage of shock after severe hemorrhage in rats. [Animal study: H2 inhalation stabilizes blood pressure until curative treatment.]
2014 Hearing Loss (Noise-Induced) PubMed Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss. [Animal study shows protective effect against auditory damage.]
2016 Sepsis PubMed Molecular Hydrogen Therapy Ameliorates Organ Damage Induced by Sepsis. [Animal study shows improved survival with H2 therapy.]
2016 Motor Deficits Tandfonline Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice. [Animal study shows benefits for muscular dystrophy.]
2016 Bladder PubMed Preventive Effect of Hydrogen Water on Detrusor Overactivity in a Rat Model of Bladder Outlet Obstruction. [Animal study shows H2 protects against bladder dysfunction.]
2009 Hearing: Auditory Hair Cells PubMed Hydrogen protects auditory hair cells from free radicals. [In vitro study: H2 prevents cell death of auditory hair cells.]
2014 Preventive Medicine PubMed Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine
2009 Metabolic Acidosis PubMed Ionized alkaline water: new strategy for management of metabolic acidosis in experimental animals. [Animal study shows safe management of acidosis.]
2009 Hangovers PubMed Electrolyzed-reduced water inhibits acute ethanol-induced hangovers in Sprague-Dawley rats. [Animal study shows H2 detox effect from ethanol.]
2017 ERW Superior to other H2 Water PubMed Electrochemically reduced water exerts superior ROS scavenging activity in HT1080 cells than equivalent hydrogen-dissolved water. [In vitro study: ERW has additional antioxidative factors, likely platinum nanoparticles, making it superior.]

Hydrogen Water Research: Comprehensive Scientific Evidence

Hydrogen-rich and ionized water have been studied extensively for their potential health benefits. Thousands of scientific articles suggest positive effects across multiple areas including skin health, anti-inflammatory responses, antioxidant protection, anti-aging, eye health, and general wellness.

IONIZED WATER USED TO CURE ATOPIC DERMATITIS: HOSPITAL REPT.

Japanese study shows ionized water cured an Atopic Dermatitis patient. Atopic dermatitis is an illness accompanied by intense itching. Its cause is unknown. It is normally an incurable-illness. 

This report is from Akashi Hospital in Tokyo, Japan. It shows how Dr. Shinkai has cured thousands of patients with atopic dermatitis using both alkaline and acidic ionized water.

Video Transcript

IONIZED WATER USED TO CURE ATHLETES FOOT, BED SORES & MORE

This report shows several more serious medical problems cured with alkaline and acidic ionized water.

Video Transcript

IONIZED WATER & PREGNANCY

Ionized water studied extensively with gestating women. Dr. Wantanabe (the top gynecologist in Japan) says both the mother and the baby benefit by drinking ionized water during pregnancy. 

ionized-water-pregnancy.jpg

QUOTE FROM TOP GEINECOLOGIST IN JAPAN, PROF. WATANABE IFAO, WATANABE HOSPITAL

"The main reason for its effectiveness is that this water can neutralize toxins. When given antioxidant water to pre-eclamptic toxemia cases, the results are most significant. During my long years of servicing the pre-eclamptic toxemia cases, I found that the women with pre-eclamptic toxemia who consumed antioxidant water tend to deliver healthier babies with stronger muscles. A survey report carried out on babies in this group showed intelligence above average."

CONTROLLED EXPERIMENTS STARTED IN JAPAN

The ionized water used in many experiments ionized water from a water ionizer or something like an alkaline pitcher

MICE EXPERIMENTS:

These experiments with mice show the positive effects found by water ionizer research in Japan and Korea. The video shows impressive results using ionized water with diabetes, cancer, high blood pressure and obesity in mice and rats. 

Video Transcript

CHICKEN EXPERIMENTS:

Alkaline ionized water has made significant improvements in the overall health and immune systems of chickens.

Video Transcript

BENEFITS OF MOLECULAR HYDROGEN (12-MINUTE VIDEO)

How Molecular Hydrogen Helps to Heal & Prevent Diseases:

  • Molecular hydrogen lowers oxidative stress. Oxidative stress and inflammation are two of the worst mechanisms for destroying human health. 
  • Molecular hydrogen alleviates inflammation, which is the underlying cause to many diseases. 
  • Molecular hydrogen brings the body into balance.
  • Some animal research shows that molecular hydrogen actually has the potential to prevent oxidative stress related injuries or diseases from occurring.
  • Molecular hydrogen protects the mitochondria.
  • Molecular hydrogen has no known disadvantages to health or warnings.
  • It permeates every membrane in your body.
  • When not needed, it simply evaporates.

Who Can Consume Molecular Hydrogen?

Anybody can have it: a pregnant mother, a child, a baby, the elderly, everybody. It even positively affects the unborn child.